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Clinical Studies

The positive effects of lactoferrin on acne has been proven in clinical studies on acne sufferers who showed visible changes including fewer blemishes, a reduction in the amount of redness and less oiliness.

The median improvement was:

The positive effects of lactoferrin on acne

Below are the results of example consumer and clinical research studies proving the benefits of lactoferrin as a skin treatment on both Asian and Caucasian skin types when consumed daily over a period of 4 to 8 weeks.

Consumer research study 1 – test market group

Evaluating lactoferrin as a dietary supplement for the support of a healthy complexion

44participants, for whom other so called ‘acne cures’ had proven ineffective, but who shared the desire to be acne-free, were enrolled in the study  (223 males and 21 females).  For 8 weeks the subjects were supplemented with 200mg lactoferrin.  Photographs taken by an independent photographer were blinden and evaluated by an independent dermatologist.

Subject data were collected at week 0 (baseline), which occurred before supplementation started, as well as at weeks 2, 4 and 8.  The number of blackheads (open comedones) and non-blackheads (including whiteheads, closed comedones, papules, pustules and nodulocystic lesions) were counted on the forehead, left cheek, right cheek, chin and nose.  For each subject, blackheads and non-blackheads were summed over the facial regions each week.

  • After stopping lactoferrin supplementation at week 8, the number of blemishes started to increase as measured by an increased number of blemishes at week 12.
  • Over 76% of the participants observed visible improvements, including fewer blemishes, a reduction in the amount of redness and less oiliness.
  • help: clear skin 1 - female 10
  • help: clear skin 1 - male 13
  • help: clear skin 1 - male 31
  • help: clear skin 1 - male 43

Consumer research study 2 – test market group

Evaluating the effectiveness of lactoferrin in a dietary supplement regimen

Forty-two participants were enrolled in the study and divided into 3 groups.  The groups were stratified for gender and baseline acne severity.  All groups were supplemented with Lactoferrin for 7 successive weeks.  Group 1 received a total amount of 25mg lactoferrin per day; Group 2 received a total amount of 100mg lactoferrin per day; Group 3 received a total amount of  200mg lactoferrin per day.

Subjects had front profile photographs taken by an independent photographer.  Photographs were blinded and evaluated by a dermatologist.  Subject data ere reported at week 0 (baseline) and week 8.

  • Praventic 2a
  • Praventic 2b
  • Praventic 2c
  • Praventic 2d
  • Praventic 2e
  • Praventic 2f
  • Praventic 2g

Clinical research study 1 – effectiveness on ethnic skin types

Evaluating the effectiveness of lactoferrin on ethnic skin types

1 dosage study: 200mg lactoferrin, twice daily (no placebo)
14 subjects (4 male and 10 female) with mild to moderate acne, 15-27 years (av. 21)
Examination and photographs at week 0, 2,4,8 and 12 weeks.  Interviewed on self -assessment of acne, complexion and self esteem/confidence
Photographs and data assessed by an independent dermatologist

  • Praventic 3a
  • Lactoferrin 3b
  • Lactoferrin 3e
  • Lactoferrin 3d
  • Lactoferrin 3c